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KMID : 0359320130530030189
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Korean Journal of Veterinary Research
2013 Volume.53 No. 3 p.189 ~ p.192
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Metastatic thyroid C-cell carcinoma in a beagle dog
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Lee So-Ra
Lee Mi-kyoung
Youp Kyoung-A
Lee Ah-Ra
Won Sung-Jun
Kim Myung-Chul
Kim So-Yeon
Kim Yong-Baek
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Abstract
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An adult beagle dog was presented with a cervical mass detected by palpation and computed tomography. Fine needle aspirates revealed numerous epithelial cells with plasmacytoid appearance and frequent naked nuclei. Histologically, the mass consists of multiple packets of neoplastic cells and extensive areas of necrosis and fibrosis. Neoplastic cells were also found in submandibular lymph nodes. Immunohistochemistry showed that neoplastic cells were positive for calcitonin and negative for thyroglobulin. Based on these findings, the cervical mass was diagnosed as thyroid C-cell carcinoma. Almost one year after the surgical excision, the dog remains healthy without any symptom of recurrence or metastasis.
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KEYWORD
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calcitonin, C-cell carcinoma, dog, metastasis, thyroid
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